Miscellaneous Immobilized Affinity Ligands
Cayman Chemical 2-ImInobIotIn 10mg
A selective inhibitor of HDAC3 (IC50 289 nM) that alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma
AdipoGen LPS from E. coli EH100 (Ra) TLRpure Sterile Solution (500 ug)
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution (500 ug), Adipogen Life Sciences. Chemical. Isolated and purified from E. coli strain EH100. Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by LPS-binding protein (LBP). Re-form LPS and lipid A, but not S-form LPS, are capable of inducing TNF-alpha responses also in the absence of CD14. LPS, synthesized by most wild-type (WT) Gram-negative bacteria (S-form LPS), consists of three regions, the O-polysaccharide chain, which is made up of repeating oligosaccharide units, the core oligosaccharide and the lipid A, which harbors the endotoxic activity of the entire molecule.
Sigma Aldrich Fine Chemicals Biosciences Lipopolysaccharides from Escherichia coli O111:B4 purified by ion-exchange chromatography, TLR ligand tested, MFCD00164401
Lipopolysaccharides from Escherichia coli O111:B4 purified by ion-exchange chromatography, TLR ligand tested
Sigma Aldrich Fine Chemicals Biosciences Lipopolysaccharides from Escherichia coli O111:B4 purified by phenol extraction, MFCD00164401
Lipopolysaccharides from Escherichia coli O111:B4 purified by phenol extraction
Enzo Life Sciences MALP-2 (BULK) (500µg)
MALP-2 was originally isolated from Mycoplasma fermentans. This MALP-2 corresponds to the originally isolated isomer, which expresses potent endotoxin-like activity and approaches in certain experimental systems the toxicity of LPS. For description of the stereochemistry of MALP-2. MALP-2 signalling, unlike that of LPS, is not transduced via TLR4, but is induced via TLR2 and TLR6 signalling. BULK size (500μg) of biologically active, pyrogen-free and sterile MALP-2 for in vitro and animal in vivo studies. Alternative name: Macrophage activating lipopeptide 2, S-[2,3-bis(Palmityloxy)-(2R)-propyl-cysteinyl-GNNDESNISFKEK]. Formula: C99H167N19O30S. MW: 2135.2. Formulation: Liquid. Pyrogen-free, sterile solution in 33% (v/v) 2-propanol/water. Handling: Avoid accidental injection, extreme care should be taken with hypodermic syringes. Avoid inhalation and prevent this compound from entering the bloodstream. Avoid freeze/thaw cycles.
Enzo Life Sciences GW-9662 (50mg). CAS: 22978-25-2
Potent, selective and irreversible PPARγ antagonist. Blocks the PPARγ-induced differentiation of monocytes to osteoclasts by >90% at a dose of 0.1µM. Much more potent antagonist than BADGE (ALX-270-353). Can be used to antagonize the effects of PPARγ agonists in a variety of cell types. Alternative name: 2-Chloro-5-nitrobenzanilide. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (50mg/ml), 100% ethanol (10mg/ml) or dimethyl formamide. Insoluble in water. Long Term Storage: Ambient.
Enzo Life Sciences GW-9662 (10mg). CAS: 22978-25-2
Potent, selective and irreversible PPARγ antagonist. Blocks the PPARγ-induced differentiation of monocytes to osteoclasts by >90% at a dose of 0.1µM. Much more potent antagonist than BADGE (ALX-270-353). Can be used to antagonize the effects of PPARγ agonists in a variety of cell types. Alternative name: 2-Chloro-5-nitrobenzanilide. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (50mg/ml), 100% ethanol (10mg/ml) or dimethyl formamide. Insoluble in water. Long Term Storage: Ambient.
Gold Biotechnology Inc Nickel Agarose Beads (High Density) 25 mL
Nickel Agarose Resin is available in bulk or in prepacked columns. It has a binding capacity of >25 mg/ml with approximately 60 kDa protein. In addition, it allows for purification of proteins under native or denaturing conditions. GoldBio Nickel Agarose works very well with the His-Tag Buffer Set.
Gold Biotechnology Inc Nickel Agarose Beads (High Density) 50 mL
Nickel Agarose Resin is available in bulk or in prepacked columns. It has a binding capacity of >25 mg/ml with approximately 60 kDa protein. In addition, it allows for purification of proteins under native or denaturing conditions. GoldBio Nickel Agarose works very well with the His-Tag Buffer Set.
Sigma Aldrich Fine Chemicals Biosciences Zymosan A from Saccharomyces cerevisiae for inducing inflamatory response, 58856-93-2, MFCD00082157
Zymosan A from Saccharomyces cerevisiae for inducing inflamatory response
Associates of Cape Cod Inc CHROMOGENIC LAL 25 VL X 60 TS
PYROCHROME CHROMOGENIC LAL WITH GLUCASHIELD BUFFER, ENDOTOXIN-SPECIFIC ASSAY, 25 VIALS EACH OF LAL AND BUFFER
Sigma Aldrich Fine Chemicals Biosciences Lipopolysaccharides from Escherichia coli O111:B4, 297-473-0, MFCD00164401, 10 x 1mg
γ-irradiated, BioXtra, suitable for cell culture, Synonym: LPS; This LPS serotype has been used to stimulate B-cells and induce NOS in human hepatocytes.